abstract：BACKGROUND:We assessed the auditory function of 94 patients with type 2 diabetes mellitus and 94 age- and sex-matched healthy subjects. METHODS:To study the influence of the clinical characteristics of the disease on the auditory function, after a clinical interview with ophthalmological assessment, subjects were eval...

journal_title：Archives of medical research

authors： Díaz de León-Morales LV,Jáuregui-Renaud K,Garay-Sevilla ME,Hernández-Prado J,Malacara-Hernández JM

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:This study investigated the association of working conditions and lifestyle with the development of increased serum gamma-glutamyltransferase (GGT) in Japanese workers. METHODS:A follow-up study was carried out on workers of a telecommunication enterprise who received their first annual health check-up betw...

journal_title：Archives of medical research

authors： Higashikawa A,Suwazono Y,Okubo Y,Uetani M,Kobayashi E,Kido T,Nogawa K

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Estrogens exert profound effects on target tissues. These effects are mediated by two estrogen receptors (ER(alpha) and ER(beta)) that bind to specific DNA sequences in estrogen-dependent genes. Other molecules such as growth factors, transcription factors and some oncoproteins might interact with the estrog...

journal_title：Archives of medical research

authors： Castro I,Arias J,Flores H,Barrón A

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Behcet's disease (BD) is a multisystem disorder characterized by a relapsing inflammatory process of unknown etiology. It is well known that atherothrombosis in systemic inflammatory disorders is closely related to coagulation and lipid metabolism abnormalities. The purpose of this study was to investigate s...

journal_title：Archives of medical research

authors： Musabak U,Baylan O,Cetin T,Yesilova Z,Sengul A,Saglam K,Inal A,Kocar IH

更新日期：2005-07-01 00:00:00

abstract：:The pathological sequence for type 2 diabetes is complex and entails many different elements that act in concert to cause that disease. This review proposes a sequence of events and how they interact by a careful analysis of the human and animal model literature. A genetic predisposition must exist, although to date v...

journal_title：Archives of medical research

authors： Leahy JL

更新日期：2005-05-01 00:00:00

abstract：:Behavioral changes and adherence to pharmacological treatment are essential for improving the prognosis in chronic illness. Lack of adherence to treatment is a common problem in every practice and many patients drop out of care prematurely. The present article is a review of our knowledge regarding adherence to treatm...

journal_title：Archives of medical research

authors： Lerman I

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:This study aims to investigate the efficacy of fluoxetine and paroxetine on the levels of depression-anxiety, quality of life, disability, and metabolic control in type II diabetes mellitus (DM) patients. METHODS:The patients were first applied the Hospital Anxiety-Depression Scale (HADS). After a psychiatr...

journal_title：Archives of medical research

authors： Gülseren L,Gülseren S,Hekimsoy Z,Mete L

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Polymorphisms which are inherited alterations in the activity of cytochrome P450 1B1 (CYP1B1), catechol O-methyltransferase (COMT), manganese superoxide dismutase (MnSOD) hold the potential to define differences in estrogen metabolism and, thereby, possibly explain inter-individual differences in cancer susc...

journal_title：Archives of medical research

authors： Kocabaş NA,Sardaş S,Karakaya AE

更新日期：2005-01-01 00:00:00

abstract：:One of the mechanisms that Entamoeba histolytica uses to evade host immune response is inhibition of the polymorphonuclear (PMN) leukocyte respiratory burst. In studies previously conducted in a model used in our laboratory, we observed that when treating trophozoites with different zinc concentrations certain amebic ...

journal_title：Archives of medical research

authors： Vega-Robledo GB,Leandro E,Silva R,Olivos A,Rico G

更新日期：2005-01-01 00:00:00

abstract：:Pathogenesis of the development of sepsis is highly complex and has been the object of study for many years. The inflammatory phenomena underlying septic shock are described in this review, as well as the enzymes and genes involved in the cellular activation that precedes this condition. The most important molecular a...

journal_title：Archives of medical research

authors： López-Bojórquez LN,Dehesa AZ,Reyes-Terán G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:We tested the hypothesis that endurance over-training could alter the favorable effects of well-tolerated training on lipid profile. METHODS:At weeks 1, 6, 15, 26, 36, and 47 of the training program, blood was drawn to test lipid profile of 20 endurance-trained rowers. Diet and caloric intake were controlle...

journal_title：Archives of medical research

authors： Petibois C,Déléris G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:The main objectives in this work were to determine whether the relationship between serum testosterone concentration and electroencephalography (EEG) develop mental change observed in human males is also present in Macaca mulatta and, if so, to determine which frequency bands are involved and which regions c...

journal_title：Archives of medical research

authors： Poblano A,Hernández-Godínez B,Arellano A,Arteaga C,Elías Y,Morales J,Poblano R,Poblano-Alcalá A

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Injecting a neurotoxin virus into ovary of adult rats has provided morphologic evidence of a multisynaptic neural pathway between ovary and central nervous system (CNS). Vagus nerve is one of the pathways used by CNS to send and receive information to and from the ovary. METHODS:The present study analyzed w...

journal_title：Archives of medical research

authors： Morales-Ledesma L,Betanzos-García R,Domínguez-Casalá R

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:The paper analyzed the impact of war, the most pernicious of social evils, taking into consideration intensity of change in rate of suicide in the southwestern region of Croatia during the war and including three distinctly specific intervals, two peacetime-one pre-war (1986-1990) and one post-war (1996-2000...

journal_title：Archives of medical research

authors： Bosnar A,Stemberga V,Cuculic D,Zamolo G,Stifter S,Coklo M

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:It is well documented that Giardia duodenalis undergoes surface antigenic variation both in vivo and in vitro. Proteins involved have been characterized and referred to as VSP (variable surface protein). METHODS:Two cloned cDNA inserts of 0.45 and 1.95 kb were obtained from G. duodenalis expression library ...

journal_title：Archives of medical research

authors： Bermúdez-Cruz RM,Ortega-Pierres G,Ceja V,Coral-Vázquez R,Fonseca R,Cervantes L,Sánchez A,Depardón F,Newport G,Montañéz C

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:We previously showed by using biochemical parameters that male Sprague-Dawley rats receiving a single intraperitoneal (i.p.) administration of alloxan (120 mg/kg body weight) with no further treatment recovered endocrine pancreatic function after 12 days. METHODS:Male Sprague-Dawley rats received an i.p. in...

journal_title：Archives of medical research

authors： De Haro-Hernández R,Cabrera-Muñoz L,Méndez JD

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although several studies have identified factors associated with bone mineral density (BMD), little research is available on Mexican women. METHODS:A cross-sectional study was conducted in 1,622 female workers between 20 and 80 years of age at the Mexican Social Security Institute (IMSS), an integral part o...

journal_title：Archives of medical research

authors： López-Caudana AE,Téllez-Rojo Solís MM,Hernández-Avila M,Clark P,Juárez-Márquez SA,Lazcano-Ponce EC,Salmerón-Castro J

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:The frequency of neurologic manifestations of the central nervous system (CNS) as a defining disease of acquired immunodeficiency syndrome (AIDS) (neurologic manifestation defining disease [NMDD-AIDS]) varies according to geographic region. The aim of this study was to determine its prevalence among patients...

journal_title：Archives of medical research

authors： Castro-Sansores CJ,Góngora-Biachi RA,González-Martínez P

更新日期：2004-01-01 00:00:00

abstract：:Acute myeloid leukemia (AML) is a clonal disorder defined by the accumulation of abnormally differentiated myeloid cells that are not mature; any myeloid lineage can be affected and the extent of maturation of the leukemia blasts can also vary. Because mature blast cells of AML have very limited proliferative capacity...

journal_title：Archives of medical research

authors： Hope KJ,Jin L,Dick JE

更新日期：2003-11-01 00:00:00

abstract：:The fundamental principle of stem cell biology is that cells with the potential for both self-renewal and terminal differentiation into one or more cell types may be found in a given tissue. The corollary of this principle is that the stem cells give rise to tissues in which they reside, the so-called expected tissues...

journal_title：Archives of medical research

authors： Horwitz EM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Angiotensin converting enzyme (ACE) inhibitors and angiotensin II AT1-receptor antagonists prolong survival in experimental postischemic heart failure (CHF) in rats. The aim of this study was to investigate whether potential beneficial effects of early and long-term therapy with low doses of captopril or los...

journal_title：Archives of medical research

authors： Martínez LA,Villalobos-Molina R

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Studies in platelet of 5-HT uptake transporters have been performed using binding assay methodology designed for ligand-receptor interactions; however, uptake transporters present requirements that may question the validity of these particular binding assays. METHODS:To explore methodologic aspects that may...

journal_title：Archives of medical research

authors： Jurado N,Torner C,Heinze G,López G,Mendoza-Sotelo J,Lazo-Langner A,Moreno J

更新日期：2003-09-01 00:00:00

abstract：:Gene therapy holds great promise. Somatic gene therapy has the potential to treat a wide range of disorders, including inherited conditions, cancers, and infectious diseases. Early progress has already been made in the treatment of a range of disorders. Ethical issues surrounding somatic gene therapy are primarily tho...

journal_title：Archives of medical research

authors： Smith KR

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Pyruvate kinase isozymes in human breast tumor tissue were compared in this study with normal human breast tissue. Two forms of pyruvate kinase present in normal and tumor human breast were purified by ammonium sulfate precipitation, dialysis, gel filtration, ion exchange, and affinity chromatography. Molecu...

journal_title：Archives of medical research

authors： Yilmaz S,Ozan S,Ozercan IH

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Cisplatin is a widely used chemotherapy agent that has several adverse effects, such as ototoxicity. Evaluation of hearing loss due to cisplatin therapy in children is difficult. The purpose of this study was to compare the validity of distortion product otoacoustic emissions (DPOAEs) with pure tone audiomet...

journal_title：Archives of medical research

authors： Toral-Martiñón R,Shkurovich-Bialik P,Collado-Corona MA,Mora-Magaña I,Goldgrub-Listopad S,Shkurovich-Zaslavsky M

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Mexico has a high prevalence of short stature (SS) population; thus, body mass index (BMI) criteria for diagnosis of obesity should be different from that in a tall stature (TS) population. The aim of this study was to determine whether SS at the same BMI would have greater body fat mass than those with TS. ...

journal_title：Archives of medical research

authors： López-Alvarenga JC,Montesinos-Cabrera RA,Velázquez-Alva C,González-Barranco J

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:A comprehensive understanding of the immune response induced by Mycobacterium bovis Bacille Calmette-Guérin in activation of protective T cells against tuberculosis is important to develop effective therapies to combat this disease. In this study, our experiments were designed to determine effects of transfo...

journal_title：Archives of medical research

authors： Hernández-Garay M,Méndez-Samperio P

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Thymectomy is considered the most effective treatment for achieving sustained improvement as well as remission in patients with myasthenia gravis (MG), and most neurologists favor the use of this procedure. The main focus of many current studies is to determine response-predicting factors. METHODS:Clinical ...

journal_title：Archives of medical research

authors： Remes-Troche JM,Téllez-Zenteno JF,Estañol B,Garduño-Espinoza J,García-Ramos G

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine concentrations of tumor necrosis factor-alpha (TNF-alpha) in normal, painful, and asymptomatic human dental pulps. METHODS:Pulps were obtained from three groups of teeth, including healthy teeth, asymptomatic teeth with caries and/or large restoration, and symptomatic ...

journal_title：Archives of medical research

authors： Pezelj-Ribaric S,Anic I,Brekalo I,Miletic I,Hasan M,Simunovic-Soskic M

更新日期：2002-09-01 00:00:00

abstract：:Thanks to the results of the multiple completed and ongoing genome sequencing projects and to the newly available recombination-based cloning techniques, it is now possible to build gene repositories with no precedent in their composition, formatting, and potential. This new type of gene repository is necessary to add...

journal_title：Archives of medical research

authors： Brizuela L,Richardson A,Marsischky G,Labaer J

更新日期：2002-07-01 00:00:00

abstract：:Scorpion venom contains different types of peptides toxic to a variety of organisms whose molecular targets have been described as mainly ion-channels of excitable cells where they cause impairment of function. Based on mouse, cricket, and crustacean bioassays, specific toxins for each group of animals have been found...

journal_title：Archives of medical research

authors： Possani LD,Corona M,Zurita M,Rodríguez MH

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Coronary artery disease is the significant cause of morbidity and mortality today. The treatment of coronary artery disease is improving, but its prevalence is increasing. Both primary and secondary prevention measures are of vital importance. METHODS:In this study, vitamin C, total antioxidant status, malo...

journal_title：Archives of medical research

authors： Tamer L,Sucu N,Polat G,Ercan B,Aytacoglu B,Yücebilgiç G,Unlü A,Dikmengil M,Atik U

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Growth deficits are common in children with sickle cell disease. Few prospective studies are available and the pathophysiologic basis for the impaired growth is not clearly understood. Our objectives were to collect data on anthropomorphic measurements of children with sickle cell disease prospectively follo...

journal_title：Archives of medical research

authors： Silva CM,Viana MB

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Because lymphocytes from fragile X patients have been reported as hypersensitive to bleomycin-induced chromatid breaks and because the number of trinucleotide repeats in families with fragile X syndrome has a propensity to expand, we have investigated the possibility that fragile X cells may be hypersensitiv...

journal_title：Archives of medical research

authors： Wang TS,Hsieh LJ,Hsu TY,Chung CH,Li SY

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Our objective was to determine the main factors associated with increased utilization of a cervical cancer screening program (CCSP) in a population with a high mortality rate due to cervical cancer. METHODS:A population-based study was carried out in the Mexican state of Morelos, Mexico. The study populatio...

journal_title：Archives of medical research

authors： Lazcano-Ponce EC,Moss S,Cruz-Valdez A,de Ruíz PA,Martínez-León CJ,Casares-Queralt S,Hernández-Avila M

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to determine whether newborn birth weights were associated with insulin-like growth factor I (IGF-I), zinc, and leptin in preeclamptic and normotensive pregnancies. METHODS:This study was done cross-sectionally and included 15 women with moderate preeclampsia (PE group) and ...

journal_title：Archives of medical research

authors： Díaz E,Halhali A,Luna C,Díaz L,Avila E,Larrea F

更新日期：2002-01-01 00:00:00

abstract：:During the late 1940s, Alfred Jost demonstrated that mammalian sex differentiation begins in fetal testis, producing two factors necessary for the establishment of phenotypic males. Castrated embryos prior to testis differentiation led to phenotypic female differentiation. Jost proposed the existence of a testis-deter...

journal_title：Archives of medical research

authors： Merchant-Larios H,Moreno-Mendoza N

更新日期：2001-11-01 00:00:00

abstract：:Implantation is a complex spatio-temporal interaction between the genotypically different embryo and the mother. Success of this event requires the synchronization of development and effective biochemical communications from both sides. Chorionic gonadotropin (CG), which is a major embryonic signal in the primate, is ...

journal_title：Archives of medical research

authors： Srisuparp S,Strakova Z,Fazleabas AT

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:It has been recently shown that oral administration of D002, a mixture of higher aliphatic primary alcohols isolated from beeswax, inhibits rat microsomal lipid peroxidation. This justified the present attempt to investigate whether D002 also exerts antioxidant effects in humans. METHODS:The effects of D002...

journal_title：Archives of medical research

authors： Menéndez R,Más R,Amor AM,Pérez Y,González RM,Fernández J,Molina V,Jiménez S

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Annually, there are more than 6 million deaths from a type of malignant neoplasia worldwide. In developing countries, the highest rates of incidence of malignant neoplasias are uterine cervical cancer, stomach, lung, esophagus, pharynx, and liver cancers. Recent estimates on the incidence of cancer worldwide...

journal_title：Archives of medical research

authors： Tovar-Guzmán V,Hernández-Girón C,Barquera S,Rodríguez-Salgado N,López-Carrillo L

更新日期：2001-07-01 00:00:00